merck-100590.1000-glycine-cryst-c6-6c1.jpg

MERCK 100590.1000 Glycine cryst. suitable for EMPROVE CAS No. 56-40-6 (SD.M.100590.1000)

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MERCK 100590.1000 Glycine cryst. suitable for EMPROVE CAS No. 56-40-6

Description
Catalogue Number	100590
Synonyms	Gly, Aminoacetic acid, Aminoethanoic acid
Description	Glycine cryst.

Product Information
CAS number	56-40-6
EC number	200-272-2
Grade	Ph Eur,BP,ChP,JP,USP
Hill Formula	C₂H₅NO₂
Chemical formula	H₂NCH₂COOH
Molar Mass	75.07 g/mol
HS Code	2922 49 10
Structure formula Image
Quality Level	MQ500

Physicochemical Information
Density	1.161 g/cm3 (20 °C)
Melting Point	>233 °C (decomposition)
pH value	5.9 - 6.4 (50 g/l, H₂O, 20 °C)
Vapor pressure	0.0000171 Pa (25 °C)
Bulk density	920 kg/m3
Solubility	250 g/l soluble

Toxicological Information
LD 50 oral	LD50 Rat 7930 mg/kg

Safety Information according to GHS
RTECS	MB7600000
Storage class	10 - 13 Other liquids and solids
WGK	WGK 1 slightly hazardous to water
Disposal	3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.

Storage and Shipping Information
Storage	Store at +2°C to +30°C.

Transport Information
Declaration (railroad and road) ADR, RID	Kein Gefahrgut
Declaration (transport by air) IATA-DGR	No Dangerous Good
Declaration (transport by sea) IMDG-Code	No Dangerous Good

Specifications
Assay (perchloric acid titration, calculated on dried substance)	99.0 - 101.0 %
Identity (IR-spectrum)	passes test
Identity (TLC)	passes test
Appearance	white to almost white, crystalline powder
Appearance of solution (100 g/l, CO₂-free water)	clear and colorless and not more intense in color than reference solution Y₇
Acidity (50g/l, water)	5.6 - 6.6
pH (50 g/l CO₂-free water)	5.9 - 6.4
Transmittance of solution (50 g/l, water)	≥ 98.0 %
Chloride (Cl)	≤ 70 ppm
Sulfate (SO₄)	≤ 60 ppm
Fe (Iron)	≤ 10 ppm
Heavy metals (as Pb)	≤ 10 ppm
As (Arsenic)	≤ 1 ppm
Hydrolyzable substances	passes test
Related substances (TLC)	passes test
Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)	≤ 0.10 %
Ninhydrin-positive substances (LC) (ammonium (570 nm))	≤ 0.02 %
Ninhydrin-positive substances (LC) (total impurities)	≤ 1.0 %
Related substances (HPLC) (Impurity B)	≤ 0.10 %
Related substances (HPLC) (Impurity H)	≤ 0.10 %
Related substances (HPLC) (Impurity I)	≤ 0.10 %
Related substances (HPLC) (unspecified impurities)	≤ 0.10 %
Sum of impurities (Ph Eur)	≤ 0.2 %
Related compounds (HPLC) (Glycine anhydride)	≤ 0.10 %
Related compounds (HPLC) (Iminodiacetic acid)	≤ 0.10 %
Related compounds (HPLC) (Diglycine)	≤ 0.10 %
Related compounds (HPLC) (Triglycine)	≤ 0.10 %
Related compounds (HPLC) (Hexamethylenetetramine)	≤ 0.10 %
Sum of impurities (USP)	≤ 1.0 %
Methanol (HS-GC)	≤ 3000 ppm
Other residual solvents (ICH Q3C)	excluded by manufacturing process
Loss on drying (105 °C, 2 h)	≤ 0.2 %
Sulfated ash (600 °C)	≤ 0.1 %
Bacterial endotoxins	≤ 2.0 I.U./g
Total aerobic microbial count (TAMC)	≤ 10 CFU/g
Total combined yeasts/moulds count (TYMC)	≤ 10 CFU/g
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., BP, ChP, JP, USP

Global Trade Item Number
Catalogue Number	GTIN
1005900001	04027269300494
1005901000	04027269222741
1005905000	04027269222758
1005909012	04027269260668
1005909025	04027269222765

Havale ile Ödeme 5.708,79 ₺ + KDV

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