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merck-100864-fb4674.jpg

MERCK 100864.2500 Ethyl acetate suitable for use as excipient EMPROVE® CAS No.141-78-6 (SD.M.100864.2500)

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MERCK 100864.2500 Ethyl acetate suitable for use as excipient EMPROVE® CAS No.141-78-6

 

Description
Catalogue Number 100864
Synonyms Ethyl ethanoate, Acetic ester, Ethyl ester
Description Ethyl acetate
Product Information
CAS number 141-78-6
EC index number 607-022-00-5
EC number 205-500-4
Grade Ph Eur,BP,NF
Hill Formula C₄H₈O₂
Chemical formula CH₃COOC₂H₅
Molar Mass 88.11 g/mol
HS Code 2915 31 00
Structure formula Image Structure formula Image
Quality Level MQ500
Physicochemical Information
Boiling point 77 °C (1013 hPa)
Density 0.90 g/cm3 (20 °C)
Explosion limit 2.1 - 11.5 %(V)
Flash point -4 °C
Ignition temperature 460 °C
Melting Point -83 °C
Vapor pressure 97 hPa (20 °C)
Solubility 85.3 g/l
Toxicological Information
LD 50 oral LD50 Rat 5620 mg/kg
LD 50 dermal LD50 Rabbit > 18000 mg/kg
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Statement(s) H225: Highly flammable liquid and vapour.
H319: Causes serious eye irritation.
H336: May cause drowsiness or dizziness.
EUH066: Repeated exposure may cause skin dryness or cracking.
Precautionary Statement(s) P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233: Keep container tightly closed.
P240: Ground and bond container and receiving equipment.
P241: Use explosion-proof electrical/ ventilating/ lighting equipment.
P242: Use non-sparking tools.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
Signal Word Danger
RTECS AH5425000
Storage class 3 Flammable liquids
WGK WGK 1 slightly hazardous to water
Disposal 1
Strongly contaminated halogen-free organic solvents: container A.
Safety Information
Categories of danger highly flammable, irritant
Storage and Shipping Information
Storage Store at +2°C to +30°C.
Transport Information
Declaration (railroad and road) ADR, RID UN 1173 , 3, II
Declaration (transport by air) IATA-DGR UN 1173 , 3, II
Declaration (transport by sea) IMDG-Code UN 1173 , 3, II
Specifications
Assay (GC) 98.0 - 102.0 %
Identity (IR) conforms
Appearance of solution conforms
Acidity (Ph Eur, BP) conforms
Acidity (NF) conforms
Density (d 20 °C/20 °C) 0.898 - 0.902
Density (d 25 °C/25 °C) 0.894 - 0.898
Refractive index (n 20/D) 1.370 - 1.373
Cu (Copper)* ≤ 0.05 ppm
Ru (Ruthenium)* ≤ 0.05 ppm
Acetaldehyde (GC) ≤ 0.1 %
1-Ethoxy-2-methylpropane (GC) ≤ 0.1 %
Methyl compounds (GC) ≤ 0.1 %
Other impurities (GC) ≤ 0.3 %
Related substances (GC) ≤ 0.2 %
Residual solvents class 3 (ICH Q3C) < 0.5
Readily carbonizable substances conforms
Evaporation residue ≤ 0.0030 %
Water ≤ 0.10 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities).
Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Conforms to Ph Eur, BP, NF.
Global Trade Item Number
Catalogue Number GTIN
1008641000 04022536011196
1008642500 04022536011219
1008646010 04022536011240
1008646025 04022536011257
1008646190 04022536011264
1008649181 04022536011271
Etiketler
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