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MERCK 100202.2500 N,N-Dimethylformamide for headspace gas chromatography SupraSolv®. CAS No.68-12-2 (SD.M.100202.2500)

Marka : MERCK
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MERCK 100202.2500 N,N-Dimethylformamide for headspace gas chromatography SupraSolv®. CAS No.68-12-2

 

Description
Catalogue Number 100202
Synonyms DMF, N,N-Dimethylmethanamide, Formic acid dimethylamide
Description N,N-Dimethylformamide
Overview SupraSolv® solvents for headspace gas chromatography are developed particularly for the analysis of residual solvents in drug substances, excipients and drug products according to ICH, Ph Eur and USP - SupraSolv® headspace solvents are tested for all residual solvents defined by the ICH.
Product Information
CAS number 68-12-2
EC index number 616-001-00-X
EC number 200-679-5
Hill Formula C₃H₇NO
Chemical formula HCON(CH₃)₂
Molar Mass 73.09 g/mol
HS Code 2924 19 22
Structure formula Image Structure formula Image
Quality Level MQ100
Applications
Application N,N-Dimethylformamide for headspace gas chromatography SupraSolv®. CAS 68-12-2, EC Number 200-679-5, chemical formula HCON(CH₃)₂.
Physicochemical Information
Boiling point 153 °C (1013 hPa)
Density 0.944 g/cm3 (25 °C)
Explosion limit 2.2 - 16 %(V)
Flash point 57.5 °C
Ignition temperature 410 °C
Melting Point -61 °C (External MSDS)
pH value 7 (200 g/l, H₂O, 20 °C)
Vapor pressure 3.77 hPa (20 °C)
Solubility 1000 g/l soluble
Toxicological Information
LD 50 oral LD50 Rat 3010 mg/kg
LD 50 dermal LD50 Rabbit 1500 mg/kg
Safety Information according to GHS
Hazard Statement(s) H226: Flammable liquid and vapour.
H312 + H332: Harmful in contact with skin or if inhaled.
H319: Causes serious eye irritation.
H360D: May damage the unborn child.
Precautionary Statement(s) P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P280: Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
P303 + P361 + P353: IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.
P304 + P340 + P312: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
Signal Word Danger
RTECS LQ2100000
Storage class 3 Flammable liquids
WGK WGK 2 obviously hazardous to water
Disposal 3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Categories of danger toxic for reproduction, harmful, irritant
Storage and Shipping Information
Storage Store at +2°C to +30°C.
Transport Information
Declaration (railroad and road) ADR, RID UN 2265 , 3, III
Declaration (transport by air) IATA-DGR UN 2265 , 3, III
Declaration (transport by sea) IMDG-Code UN 2265 , 3, III
Specifications
Purity (GC) ≥ 99.8 %
Identity (IR) conforms
Evaporation residue ≤ 3.0 mg/l
Water ≤ 0.05 %
Color ≤ 10 Hazen
GC/HS (Every residual solvent of class 1 acc. ICH) ≤ 1 µg/g
GC/HS (Every residual solvent of class 2 acc. ICH) ≤ 10 µg/g
GC/HS (Every residual solvent of class 3 acc. ICH) ≤ 50 µg/g
Suitable as solvent for the analysis of residual solvents of ICH classes 1,2 and 3 according to Ph Eur und USP.
Formic acid and acetic acid are not detected.
Global Trade Item Number
Catalogue Number GTIN
1002020500 04027269573270
1002021000 04027269198053
1002022500 04027269198060
Etiketler
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